2C-B is still considered by many to be the best psychedelic to use during sex of all time. DoubleBlind is a trusted resource for news, evidence-based education, and reporting on psychedelics. We work with leading medical professionals, scientific researchers, journalists, mycologists, indigenous stewards, and cultural pioneers.
You should also always test a sample of your 2C-B using a reagent test liquid before you use it. The drug’s creator, Alexander Shulgin, suggested 2C-B was a good follow-up treatment in psychotherapy after MDMA. He suggested 2C-B as a way to open up the emotional, intuitive and archetypal area of your psyche to help solve the problems uncovered during the MDMA session.
Will 2C-B Show Up On A Drug Test?
Analysis of oral fluid samples by LC–MS/MS concentrations ranged from 1.43 to 7.73 ng/ml, with an average peak concentration of 4.19 ng/ml observed between 1 and 3 h after administration. However, results of 2C-B pharmacokinetics indicate that 2C-B can be detected in oral fluid at very low concentrations up to 16–24 h after self-administration. Unfortunately, the interpretation of 2C-B concentrations in oral fluid is extremely difficult without data from plasma (not performed in this study neither in any study involving ketamine withdrawal timeline humans). By contrast, collection of oral fluid is easy and non-invasive, and was the method selected to obtain pharmacokinetic data in this study. Anecdotally, in two subjects involved in a road accident, 2C-B has been identified in blood at concentrations of 1.6 and 14 ng/ml together with amphetamine (Busardò et al., 2017). Such novel psychedelics include the 2C-series and its structural analogs, including N-Benzylphenethylamines (NBOMes) (Tracy et al., 2017).
The Revival of Grimy Drugs
2C-B is also used for its sexual-enhancement purposes as a way to explore a deeper connection between partners and enhance libido and physical stamina. 2C-B reached mainstream popularity sometime after 1985 when MDMA was officially banned. In one of his books — PiHKAL (phenethylamines how to taper off prozac 10mg I Have Known And Loved) — he listed 2C-B among his “magic half dozen”. How long it takes for someone to come down from these drugs ultimately depends on the dosage, how frequently a person uses a drug, their weight and metabolism, and whether they use other drugs simultaneously.
-B vs. LSD
When Shulgin was hypothesizing 2C-B’s therapeutic potential, he proposed that 2C-B might be best taken at the tail end of an MDMA session. “It is as if the mental and emotional discoveries [of an MDMA experience] can be mobilized, and something done about them,” he wrote in PiHKAL. Essentially it’s a way of integrating the material that comes up during an MDMA session and bringing participants back “into their bodies” with that grounding, mescaline-like effect of 2C-B. 2C-B can come as a pill, tablet or powder, and if you do receive a dosed pill, try and find out how many milligrams it contains. If you receive 2C-B as a powder, always weigh it out on an accurate scale before ingesting.
- It’s been reported to increase tactile awareness, increase the clarity of thought, and boost mental energy and stamina.
- According to PiHKAL, 2C-B lasts between four and eight hours, and that’s pretty in line with what the 31 people who took my survey reported.
- Lower doses of around 5 mg have effects most similar to MDMA or Adderall, while the higher doses (more than 15 mg) offer formidable hallucinogenic effects comparable to LSD, psilocybin, or mescaline.
- With that said, if you’re expecting a drug test for any reason, it would be wise to avoid 2C-B.
- Quitting suddenly may result in severe adverse effects, so consulting with a medical professional can help you or a loved one detox safely.
Some report feeling happy and in tune with their surroundings, experiencing introspective thoughts and increased empathy. 2C-B is a Schedule I drug with no accepted medical drug use and a high potential for addiction. Possession of 2C-B is punishable by up to 7 years in prison, a fine, or both. When MDMA was outlawed in 1985, 2C-B became the street drug of choice for its euphoric and psychedelic effects.
The metabolism of 2C-B has been studied in experimental animals and in vivo models (Kanamori et al., 2002, 2005; Carmo et al., 2004; Theobald et al., 2007). It is generally assumed that 2C-B is metabolized mainly by the monoamine oxidase enzymes, MAO-A and MAO-B, and, to a lesser degree, by the CYP450 system (Carmo et al., 2005; Pichini et al., 2008; Kanamori et al., 2013, 2017). Currently, there are not data available describing active metabolites that could contribute to overall effects, therefore, 2C-B seems the active one while the rest are inactive or nearly so.
As mentioned previously, both concentrations and vital signs time course were similar (Figures 1A,B). Differences with respect to baseline were calculated for vital signs (SBP, DBP, and HR) and subjective effects (VAS, ARCI, and VESSPA). Maximum effects (Emax) and the time needed to reach maximum effects (tmax) were also calculated for the mentioned variables.
As soon as the drug wears off, we’re no longer in balance — causing side effects referred to as withdrawal. Some users, including Shulgin, have reported taking as much as 100 mg of 2C-B without serious side effects. However, these doses are rarely enjoyable and can even be quite scary. 2C-B is often used as an alternative to MDMA (ecstasy) at concerts, music festivals, or parties. Lower doses of 2C-B are the most similar to MDMA for creating a greater sense of connectedness with the people around you. Both substances produce a feeling of euphoria, can enhance the enjoyment of music, and stimulate the sensual feedback from touch.
2C-B is a novel psychoactive drug that alters a person’s thought process, sense of time, and emotions. Although popular for its recreational effects, 2C-B use can lead to addiction and other long-term consequences. In this article, we cover 2C-B’s effects, health risks, and the proper response during a potential bad trip or overdose. Horror stories in sensationalist media have portrayed 2C-B as a deadly, threatening drug.[50][51] And while its toxicity profile has yet to be fully established, such reports are dubious, to say the least. Aside from the fact that aggression and alcohol and acutane violence are rarely mentioned in users’ reports, 2C-B is difficult to detect in the body. So unless the compound is confirmed in a lab, it’s fair to assume that other, lesser-known drugs are responsible.
They’re used to increase focus and concentration, improve empathy and connectedness with others, and help achieve a higher level of productivity. 2C-B is not inherently addictive — however, people can form addictions to any mind-altering substance, including 2C-B. It’s not uncommon for someone to order 2C-B online only to receive something completely different in the mail. You can never trust what’s inside your pills or powders unless you test it first.
Other Members of the 2C- Family
Being in a good state of mind, with trusted friends and a safe environment before taking 2C-B reduces the risk of having a ‘bad’ trip. It’s often used as an alternative to MDMA at lower doses and an alternative to LSD in high doses. With that said, if you’re expecting a drug test for any reason, it would be wise to avoid 2C-B. There have been reports of 2C-B triggering a false-positive on amphetamine tests, but this is very rare. They can only tell you whether or not a sample contains a certain substance or not. Only a small sample of the drug is needed to run the test (the size of a grain of sand).
2C-B is a potentially illegal substance, and we do not encourage or condone the use of this substance where it is against the law. However, we accept that illegal drug use occurs, and believe that offering responsible harm reduction information is imperative to keeping people safe. For that reason, this guide is designed to ensure the safety of those who decide to use the substance.
Other people prefer to fill their own capsules using the raw powder or snorting it (insufflation). Take a lower dose than you normally would and give it time to take effect. Sometimes, bad trips are the result of adulterants (ingredients you weren’t expecting to be in there). Samples of 2C-B have been shown to contain substances such as methamphetamines, MDA, PMA, PMMA, NBOMe, or various opiates.
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